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  Latin Name Pterocarpus marsupium
English Name Indian Kino tree 
Hindi Name Vijaysaar
Part Used Heartwood

1Pterocarpus has a long history of use in India as a treatment for diabetes. Pterocarpus bark is a rich source of polyphenolic compounds that are reported to have blood sugar lowering effects in laboratory studies. It is one among the best hypoglycemic agent. Tests on mice and rabbits with alcohol and aqueous extracts of this plant have showed hypoglycemic action, probably by hindering the absorption of glucose in the intestine.

2Anti-diabetic activity of various subfractions of the alcohol extract of the bark of Pterocarpus marsupium Roxb. was evaluated in alloxan-induced diabetic rats. It is found that extract of Pterocarpus marsupium exhibits significant antidiabetic activity and corrects the metabolic alterations in diabetic rats and this activity may resemble insulin-like properties.

3Aqueous extract of P. marsupium at both doses, i.e., 100 and 200 mg/kg, decreased the fasting and postprandial blood glucose in type 2 diabetic rats. The 200 mg/kg had more pronounced effect on postprandial hyperglycemia. The drug also improved the body weight of diabetic animals. Cytokine TNF-α was found to be elevated in untreated diabetic rats due to chronic systemic inflammation. The aqueous extract at both doses significantly (P < 0.001) decreased the elevated TNF-α level in type 2 diabetic rats.


References:

 

1. The Wealth of India, Raw materials, Vol-8: Ph-Re, edition-2005, page-302-305
2. PMID: 16397913, Phytother Res. 2006 Jan;20(1):4-8.
3. PMID: 21189913, Indian J Pharmacol. 2010 Dec;42(6):392-6.


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